Interstate 59 (I-59) is a north–south highway, with a length of just over 445 miles. It begins north of Slidell, Louisiana, to Wildwood, Georgia. Major cities along the route include Picayune, MS, Hattiesburg, Laurel, MS, Meridian, MS, Tuscaloosa, AL, Birmingham, AL, Gadsden, AL, and Fort Payne, AL. I-59 is one of the few Interstate highways that parallel an older US highway, in this case Highway 11, for its entire route. Despite being a north-south route, I-59 runs diagonally, from southwest to northeast.